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Neuro Probe.jpg

美国Neuro Probe公司专业提供用于趋化实验的耗材(Transwell),更好地服务于药筛和基础实验研究领域。着重开发研究细胞活性实验相关的耗材,从第一代用于趋化实验的Boyden Chamer(单孔小室)到48微孔板的趋化小室,再到今天的ChemTx System他们始终与科学实验的步伐保持一致,追求创新,不断地开发新产品以满足多样化的实验需求。

 

Neuro Probe was founded in the late 1960’s with an initial focus on the development and manufacture of chronic stereotactic equipment. In the early 1970’s, corporate growth and diversification lead to the development and production of chemotactic instruments, beginning with the modified Boyden chamber and then assorted blind well chambers. In 1980, the 48-well microchemotaxis chamber was developed, in collaboration with Dr. Edward Leonard and Dr. Werner Falk working at the National Institutes of Health. This chamber has become a standard in the field and has served as a basis for the development of many new products. Most recently introduced is the ChemoTx® system. Please visit the Products section of our website for more information on specific products.

 

Neuroprobe的主要产品包括:

ChemoTx®

Chemotaxis Chambers

Single Well Chambers

Filters

Replacement Gaskets

Chemotaxis Accessories

Protein Crystallography

Cell Settling Chambers

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艾美捷科技有限公司

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List Labs.jpg

List Labs公司成立于1978年,位于美国加州硅谷,是一家专业提供各类微生物Toxin的生物技术公司。

 

Our company was founded in 1978 by Linda Shoer. Cholera toxin, the first product, was sought after by those doing research in signal transduction and by others using the toxin B subunit to label neurons. At that time there were no commercial suppliers of this toxin. Our company has always focused on quality bacterial toxins, which you can depend on for your research. Because toxins have been the basis for many vaccines, List Labs products have supported vaccine development. List Labs was the first to commercialize many bacterial toxins for research, including C.difficile toxins and pertussis toxin. Today, we remain uniquely focused on manufacturing, offering and supporting a wide range of bacterial products.

 

List Labs' heart is in the science and the discovery of innovative reagents. Our office is located in Campbell, California, in Silicon Valley. We serve the global research community with an expanding group of distributors. Years of experience translate into expertise in the production, shipment and handling of dangerous goods. If you have questions about any of our products or services, contact us.

 

List Biological Labs的主要产品包括:

Anthrax Toxins

Antisera & Antibodies

Botulinum Toxins

Cholera Toxins

Difficile Toxins

Diphtheria Toxin & Crm

Exotoxin A

Fret Peptides, Native Substrates & Receptors

Lipopolysaccharides

Pertussis Toxins & Virulence Factors

Shiga Toxins

Staphylococcal Toxins

Tetanus Toxins & Related Products

Toxoids

Vaccine Carrier Proteins And Adjuvants

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艾美捷科技有限公司

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ProSci.jpg

ProSci Incorporated从事抗体等科研试剂的研发、生产和销售。公司现拥有17000多种单、多克隆抗体,产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。公司的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。ProSci的抗体广销於世界30多个国家和地区,得到欧美日等生物医学界科研人员和生物制药公司的研发人员的广泛接受。ProSci直销的产品和ProSci的名字已在520多篇科研论文中出现了1500多次,ProSci的经销商和客户都对ProSci产品的质量和服务十分满意。我们的抗体可用于免疫印迹(Western blot) ,免疫组织化学(IHC),免疫细胞化学(ICC),酶联免疫吸附实验(ELISA)和细胞流式分析(FACS)等方面。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。ProSci在美国拥有完整的免疫学试剂开发、生产、检测的生产线,包括自己的厂房和实验动物基地,可为您的研究提供信得过的抗体等科研试剂。

 

ProSci Incorporated is a privately-held biotechnology firm located in San Diego, California. A leader in its field, ProSci’s priority is to provide the highest quality monoclonal, polyclonal, and single domain antibody services in the industry. ProSci’s expertise in antibody production, immunochemistry services, and biological research is realized through customizable services, innovative products, competitive pricing, high-quality research tools, and unparalleled technical support.

 

ProSci的主要产品包括:

Primary Antibodies

Secondary Antibodies

Recombinant Proteins

Lysates

Antibody Beads

Control Antibodies

Detection Sets

Immunoblots

Peptides

Reagents

Slides

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艾美捷科技有限公司

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网站:www.amyjet.com


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AllerMAbs.jpg

艾乐美生物科技有限公司(AllerMAbs Co., Ltd.)成立于2015年,是台湾一家专注于生产高亲和力、高纯度并具有过敏原特异性的嵌合人类IgE单克隆抗体的生物公司。公司创办人团队在科研过程中发现市面上缺乏多样的IgE单克隆抗体,特別是具有过敏原特异性的人IgE 单抗。如果能制备出这种抗体,将有助于IgE 相关领域的研究工作。因此,AllerMAbs公司团队开始思考与研究利用基因克隆动物来制造人类 IgE 抗体的可行性,经过数年的努力于 2014年开发出人类IgE 抗体基因嵌入小鼠,通过杂交瘤技术 (Hybridoma technology),成功地研制出分泌嵌合人类IgE 单抗的 IgE 杂交瘤与纯化 IgE 抗体。经测试,此种嵌合人类IgE 单抗的物化性质与对免疫细胞的活性,皆与人类IgE 抗体一致,研究成果于2015 年发表在国际学术期刊上。

 

AllerMAbs的产品解决了目前人类IgE抗体不易制备的问题,让嵌合人类IgE抗体可以成为人类IgE抗体的替代品,并提供一个更稳定、更符合血清IgE检测系统的校正品,让临床血清IgE的检测结果更加准确与可靠。

 

其利用动物基因转殖技术,将组成人类IgE抗体分子的ε重链(Heavy chain)和κ轻链(Light chain)的编码基因(Encoding genes),分別嵌入(Knock-in)小鼠胚胎干细胞(Embryonic stem cells, ES cells)的γ1重链和κ轻链基因的位置,接着把胚胎干细胞分別植入孕母鼠体内,并将其带有嵌入基因之成鼠交互配种,最后得到带有人类IgE抗体重链和轻链基因的基因嵌入小鼠(HεκKI mice),且体内能制造完整的嵌合人类IgE抗体分子。

 

技术优势

容易制备IgE杂交瘤与IgE单抗

过敏原特异性

良好的亲和力与专一性

高纯度与高稳定性

可结合至嗜碱性粒细胞上的IgE受体与刺激細胞

可大量生产与高浓度制备

非人类血液来源(相较于血清IgE抗体)

适合用作检测用的校正品

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